Before the colts are three, they're two years old. The Breeder's Cup Juvenile is held in November the year before. Uncle Mo won in 2010 (video); Street Sense had won in 2006 before winning the Kentucky Derby the following year. Also, the American Champion Two-Year-Old Colt is awarded as part of the Eclipse Awards (which also has an award for fillies); Uncle Mo won in 2010; Street Sense had won in 2006.
The major prep races leading up to the Kentucky Derby begin at the end of March and run through April; all are 9 furlongs on dirt, except the Blue Grass Stakes, which is now run on synthetic polytrack.
- The Wood Memorial Stakes (top three) is held in mid-April at Aqueduct Racetrack in New York. In 2011, Uncle Mo was heavily favored to win, but in a big upset showed while Toby's Corner won and Arthur's Tale placed (video). In the past, 11 winners have gone on to win the Kentucky Derby, four of whom captured the Triple Crown.
- The Arkansas Derby (top three) is held in April at Oaklawn Park in Hot Springs, Arkansas. In 2011, Archarcharch won (video).
- The Blue Grass Stakes (top three) is held at Keeneland in Lexington, Kentucky. Brilliant Speed won in 2011 (video).
- The Florida Derby (top three) is held at the end of March or the beginning of April. In 2011, Dialed In won (video).
- The Louisiana Derby (top three) is held in early March at Fair Grounds in New Orleans, Louisiana. In 2011, Pants on Fire won (video).
- The Santa Anita Derby (top three) is held in April at Santa Anita Park in California north of Los Angeles. The winner in 2011 was Midnight Interlude (video).
- The Illinois Derby (top three) is held in April at Hawthorne outside Chicago, Illinois. Joe Vann won in 2011 (video).
Other notable prep races include the Tropical Park Derby (January, 2011), Fountain of Youth Stakes(March), Tampa Bay Derby (March), and Holy Bull Stakes (April) in Florida; the San Felipe Stakes (March) in California; and the Southwest Stakes (February) and Rebel Stakes (March) in Arkansas.